Targeted disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate oligosaccharides

Acquisition of a mucoid phenotype by Pseudomonas sp. in the lungs of cystic fibrosis (CF) patients, with subsequent over-production of extracellular polymeric substance (EPS), plays an important role in mediating the persistence of multi-drug resistant (MDR) infections. The ability of a low molecula...

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Foilsithe in:NPJ Biofilms Microbiomes
Main Authors: Powell, Lydia C., Pritchard, Manon F., Ferguson, Elaine L., Powell, Kate A., Patel, Shree U., Rye, Phil D., Sakellakou, Stavroula-Melina, Buurma, Niklaas J., Brilliant, Charles D., Copping, Jack M., Menzies, Georgina E., Lewis, Paul D., Hill, Katja E., Thomas, David W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026129/
https://ncbi.nlm.nih.gov/pubmed/29977590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41522-018-0056-3
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