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Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains

Seasonal influenza vaccines elicit antibody responses that can prevent infection, but their efficacy is reduced in the elderly. While a subset of elderly individuals can still mount sufficient vaccine-induced antibody responses, little is known about the properties of the vaccine-induced antibody re...

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Détails bibliographiques
Publié dans:Clin Immunol
Auteurs principaux: Ju, Chia-Hsin, Blum, Lisa K., Kongpachith, Sarah, Lingampalli, Nithya, Mao, Rong, Brodin, Petter, Dekker, Cornelia L., Davis, Mark M., Robinson, William H.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026060/
https://ncbi.nlm.nih.gov/pubmed/29410330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2018.01.011
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