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Identification of Functional Anti-Staphylococcus aureus Antibodies by Sequencing Patient Plasmablast Antibody Repertoires

Infection by Staphylococcus aureus is on the rise, and there is need for a better understanding of host immune responses that combat S. aureus. Here we use DNA barcoding to enable deep sequencing of the paired heavy- and light-chain immunoglobulin genes expressed by individual plasmablasts derived f...

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Detalhes bibliográficos
Main Authors: Lu, Daniel R, Tan, Yann-Chong, Kongpachith, Sarah, Cai, Xiaoyong, Stein, Emily A., Lindstrom, Tamsin M, Sokolove, Jeremy, Robinson, William H
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066023/
https://ncbi.nlm.nih.gov/pubmed/24589749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2014.02.010
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