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T cells establish and maintain CNS viral infection in HIV-infected humanized mice

The human brain is an important site of HIV replication and persistence during antiretroviral therapy (ART). Direct evaluation of HIV infection in the brains of otherwise healthy individuals is not feasible; therefore, we performed a large-scale study of bone marrow/liver/thymus (BLT) humanized mice...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Honeycutt, Jenna B., Liao, Baolin, Nixon, Christopher C., Cleary, Rachel A., Thayer, William O., Birath, Shayla L., Swanson, Michael D., Sheridan, Patricia, Zakharova, Oksana, Prince, Francesca, Kuruc, JoAnn, Gay, Cynthia L., Evans, Chris, Eron, Joseph J., Wahl, Angela, Garcia, J. Victor
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026008/
https://ncbi.nlm.nih.gov/pubmed/29863499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI98968
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