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HIV-1 infection, response to treatment and establishment of viral latency in a novel humanized T cell-only mouse (TOM) model
BACKGROUND: The major targets of HIV infection in humans are CD4(+) T cells. CD4(+) T cell depletion is a hallmark of AIDS. Previously, the SCID-hu thy/liv model was used to study the effect of HIV on thymopoeisis in vivo. However, these mice did not develop high levels of peripheral T cell reconsti...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826870/ https://ncbi.nlm.nih.gov/pubmed/24156277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-121 |
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