T cells establish and maintain CNS viral infection in HIV-infected humanized mice

The human brain is an important site of HIV replication and persistence during antiretroviral therapy (ART). Direct evaluation of HIV infection in the brains of otherwise healthy individuals is not feasible; therefore, we performed a large-scale study of bone marrow/liver/thymus (BLT) humanized mice...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Honeycutt, Jenna B., Liao, Baolin, Nixon, Christopher C., Cleary, Rachel A., Thayer, William O., Birath, Shayla L., Swanson, Michael D., Sheridan, Patricia, Zakharova, Oksana, Prince, Francesca, Kuruc, JoAnn, Gay, Cynthia L., Evans, Chris, Eron, Joseph J., Wahl, Angela, Garcia, J. Victor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026008/
https://ncbi.nlm.nih.gov/pubmed/29863499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI98968
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