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PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity

PIM kinase family members play a crucial role in promoting cell survival and proliferation via phosphorylation of their target substrates. In this study, we investigated the role of the PIM kinases with respect to T cell responses in transplantation and tumor immunity. We found that the PIM-2 isofor...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Daenthanasanmak, Anusara, Wu, Yongxia, Iamsawat, Supinya, Nguyen, Hung D., Bastian, David, Zhang, MengMeng, Sofi, M. Hanief, Chatterjee, Shilpak, Hill, Elizabeth G., Mehrotra, Shikhar, Kraft, Andrew S., Yu, Xue-Zhong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025986/
https://ncbi.nlm.nih.gov/pubmed/29781812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95407
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