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Stabilization of Foxp3 Stability by Targeting JAK2 Enhances Efficacy of CD8 iTregs to Prevent Graft-versus-Host Disease
CD8(+) induced regulatory T-cells (CD8(+) iTregs) have been identified to suppress alloreactive immune responses and expressed Treg ontological markers as similar as CD4(+) iTregs. However, adoptive transfer of CD8(+) iTreg-based therapy is hampered by the instability of Treg specific-transcription...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6200641/ https://ncbi.nlm.nih.gov/pubmed/30242073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800793 |
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