Open chromatin dynamics reveals stage-specific transcriptional networks in hiPSC-based neurodevelopmental model

Chromatin accessibility to transcription factors (TFs) strongly influences gene transcription and cell differentiation. However, a mechanistic understanding of the transcriptional control during the neuronal differentiation of human induced pluripotent stem cells (hiPSCs), a promising cellular model...

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Veröffentlicht in:Stem Cell Res
Hauptverfasser: Zhang, Siwei, Moy, Winton, Zhang, Hanwen, Leites, Catherine, McGowan, Heather, Shi, Jianxin, Sanders, Alan R., Pang, Zhiping P., Gejman, Pablo V., Duan, Jubao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025752/
https://ncbi.nlm.nih.gov/pubmed/29631039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2018.03.014
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