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Deregulation of Negative Controls on TGF-β1 Signaling in Tumor Progression

The multi-functional cytokine transforming growth factor-β1 (TGF-β1) has growth inhibitory and anti-inflammatory roles during homeostasis and the early stages of cancer. Aberrant TGF-β activation in the late-stages of tumorigenesis, however, promotes development of aggressive growth characteristics...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Tang, Jiaqi, Gifford, Cody C., Samarakoon, Rohan, Higgins, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025439/
https://ncbi.nlm.nih.gov/pubmed/29799477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10060159
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