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Quantitative detection of single nucleotide polymorphisms for a pooled sample by a bioluminometric assay coupled with modified primer extension reactions (BAMPER)

A new method for SNP analysis based on the detection of pyrophosphate (PPi) is demonstrated, which is capable of detecting small allele frequency differences between two DNA pools for genetic association studies other than SNP typing. The method is based on specific primer extension reactions couple...

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Main Authors: Zhou, Guo-hua, Kamahori, Masao, Okano, Kazunori, Chuan, Gao, Harada, Kunio, Kambara, Hideki
格式: Artigo
語言:Inglês
出版: Oxford University Press 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC60253/
https://ncbi.nlm.nih.gov/pubmed/11574695
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