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KLF10 as a Tumor Suppressor Gene and Its TGF-β Signaling

Krüppel-like factor 10 (KLF10), originally named TGF-β (Transforming growth factor beta) inducible early gene 1 (TIEG1), is a DNA-binding transcriptional regulator containing a triple C2H2 zinc finger domain. By binding to Sp1 (specificity protein 1) sites on the DNA and interactions with other regu...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Memon, Azra, Lee, Woon Kyu
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025274/
https://ncbi.nlm.nih.gov/pubmed/29799499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10060161
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