Novel role of prostate apoptosis response-4 tumor suppressor in B-cell chronic lymphocytic leukemia

Prostate apoptosis response-4 (Par-4), a proapoptotic tumor suppressor protein, is downregulated in many cancers including renal cell carcinoma, glioblastoma, endometrial, and breast cancer. Par-4 induces apoptosis selectively in various types of cancer cells but not normal cells. We found that chro...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: McKenna, Mary K., Noothi, Sunil K., Alhakeem, Sara S., Oben, Karine Z., Greene, Joseph T., Mani, Rajeswaran, Perry, Kathryn L., Collard, James P., Rivas, Jacqueline R., Hildebrandt, Gerhard C., Fleischman, Roger A., Durbin, Eric B., Byrd, John C., Wang, Chi, Muthusamy, Natarajan, Rangnekar, Vivek M., Bondada, Subbarao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024641/
https://ncbi.nlm.nih.gov/pubmed/29695515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-10-813931
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