Novel role of prostate apoptosis response-4 tumor suppressor in B-cell chronic lymphocytic leukemia

Prostate apoptosis response-4 (Par-4), a proapoptotic tumor suppressor protein, is downregulated in many cancers including renal cell carcinoma, glioblastoma, endometrial, and breast cancer. Par-4 induces apoptosis selectively in various types of cancer cells but not normal cells. We found that chro...

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Publicado en:Blood
Autores principales: McKenna, Mary K., Noothi, Sunil K., Alhakeem, Sara S., Oben, Karine Z., Greene, Joseph T., Mani, Rajeswaran, Perry, Kathryn L., Collard, James P., Rivas, Jacqueline R., Hildebrandt, Gerhard C., Fleischman, Roger A., Durbin, Eric B., Byrd, John C., Wang, Chi, Muthusamy, Natarajan, Rangnekar, Vivek M., Bondada, Subbarao
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2018
Materias:
Lymphoid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024641/
https://ncbi.nlm.nih.gov/pubmed/29695515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-10-813931
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