Preclinical Testing of an Oncolytic Parvovirus in Ewing Sarcoma: Protoparvovirus H-1 Induces Apoptosis and Lytic Infection In Vitro but Fails to Improve Survival In Vivo

About 70% of all Ewing sarcoma (EWS) patients are diagnosed under the age of 20 years. Over the last decades little progress has been made towards finding effective treatment approaches for primarily metastasized or refractory Ewing sarcoma in young patients. Here, in the context of the search for n...

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Vydáno v:Viruses
Hlavní autoři: Lacroix, Jeannine, Kis, Zoltán, Josupeit, Rafael, Schlund, Franziska, Stroh-Dege, Alexandra, Frank-Stöhr, Monika, Leuchs, Barbara, Schlehofer, Jörg R., Rommelaere, Jean, Dinsart, Christiane
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024310/
https://ncbi.nlm.nih.gov/pubmed/29865280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10060302
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