Pediatric and Adult High-Grade Glioma Stem Cell Culture Models Are Permissive to Lytic Infection with Parvovirus H-1

Combining virus-induced cytotoxic and immunotherapeutic effects, oncolytic virotherapy represents a promising therapeutic approach for high-grade glioma (HGG). A clinical trial has recently provided evidence for the clinical safety of the oncolytic parvovirus H-1 (H-1PV) in adult glioblastoma relaps...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Josupeit, Rafael, Bender, Sebastian, Kern, Sonja, Leuchs, Barbara, Hielscher, Thomas, Herold-Mende, Christel, Schlehofer, Jörg R., Dinsart, Christiane, Witt, Olaf, Rommelaere, Jean, Lacroix, Jeannine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885093/
https://ncbi.nlm.nih.gov/pubmed/27213425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8050138
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