Preclinical Testing of an Oncolytic Parvovirus: Standard Protoparvovirus H-1PV Efficiently Induces Osteosarcoma Cell Lysis In Vitro

Osteosarcoma is the most frequent malignant disease of the bone. On the basis of early clinical experience in the 1960s with H-1 protoparvovirus (H-1PV) in osteosarcoma patients, this effective oncolytic virus was selected for systematic preclinical testing on various osteosarcoma cell cultures. A p...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Geiss, Carsten, Kis, Zoltán, Leuchs, Barbara, Frank-Stöhr, Monika, Schlehofer, Jörg R., Rommelaere, Jean, Dinsart, Christiane, Lacroix, Jeannine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691652/
https://ncbi.nlm.nih.gov/pubmed/29039746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9100301
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