Zinc-Finger Nucleases Induced by HIV-1 Tat Excise HIV-1 from the Host Genome in Infected and Latently Infected Cells

Highly active anti-retroviral therapy (HAART) cannot clear infected cells harboring HIV-1 proviral DNA from HIV-1-infected patients. We previously demonstrated that zinc-finger nucleases (ZFNs) can specifically and efficiently excise HIV-1 proviral DNA from latently infected human T cells by targeti...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Ther Nucleic Acids
Main Authors: Ji, Haiyan, Lu, Panpan, Liu, Baochi, Qu, Xiying, Wang, Yanan, Jiang, Zhengtao, Yang, Xinyi, Zhong, Yangcheng, Yang, He, Pan, Hanyu, Zhao, Lin, Xu, Jianqing, Lu, Hongzhou, Zhu, Huanzhang
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023959/
https://ncbi.nlm.nih.gov/pubmed/30195798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.04.014
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki