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Glutamate as a potential “survival factor” in an in vitro model of neuronal hypoxia/reoxygenation injury: leading role of the Na(+)/Ca(2+) exchanger

In brain ischemia, reduction in oxygen and substrates affects mitochondrial respiratory chain and aerobic metabolism, culminating in ATP production impairment, ionic imbalance, and cell death. The restoration of blood flow and reoxygenation are frequently associated with exacerbation of tissue injur...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Piccirillo, Silvia, Castaldo, Pasqualina, Macrì, Maria Loredana, Amoroso, Salvatore, Magi, Simona
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023866/
https://ncbi.nlm.nih.gov/pubmed/29955038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0784-6
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