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Glutamate as a potential “survival factor” in an in vitro model of neuronal hypoxia/reoxygenation injury: leading role of the Na(+)/Ca(2+) exchanger

In brain ischemia, reduction in oxygen and substrates affects mitochondrial respiratory chain and aerobic metabolism, culminating in ATP production impairment, ionic imbalance, and cell death. The restoration of blood flow and reoxygenation are frequently associated with exacerbation of tissue injur...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Piccirillo, Silvia, Castaldo, Pasqualina, Macrì, Maria Loredana, Amoroso, Salvatore, Magi, Simona
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023866/
https://ncbi.nlm.nih.gov/pubmed/29955038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0784-6
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