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Glutamate as a potential “survival factor” in an in vitro model of neuronal hypoxia/reoxygenation injury: leading role of the Na(+)/Ca(2+) exchanger

In brain ischemia, reduction in oxygen and substrates affects mitochondrial respiratory chain and aerobic metabolism, culminating in ATP production impairment, ionic imbalance, and cell death. The restoration of blood flow and reoxygenation are frequently associated with exacerbation of tissue injur...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Piccirillo, Silvia, Castaldo, Pasqualina, Macrì, Maria Loredana, Amoroso, Salvatore, Magi, Simona
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023866/
https://ncbi.nlm.nih.gov/pubmed/29955038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0784-6
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