Essential role of the Na(+)-Ca2(+) exchanger (NCX) in glutamate-enhanced cell survival in cardiac cells exposed to hypoxia/reoxygenation

Myocardial ischemia culminates in ATP production impairment, ionic derangement and cell death. The provision of metabolic substrates during reperfusion significantly increases heart tolerance to ischemia by improving mitochondrial performance. Under normoxia, glutamate contributes to myocardial ener...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Maiolino, Marta, Castaldo, Pasqualina, Lariccia, Vincenzo, Piccirillo, Silvia, Amoroso, Salvatore, Magi, Simona
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638850/
https://ncbi.nlm.nih.gov/pubmed/29026150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13478-x
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