A combination of ontogeny and CNS environment establishes microglial identity.

Microglia, the brain’s resident macrophages, are dynamic CNS custodians with surprising origins in the extra-embryonic yolk sac. The consequences of their distinct ontogeny are unknown but critical to understanding and treating brain diseases. We created a brain macrophage transplantation system to...

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Bibliografske podrobnosti
izdano v:Neuron
Main Authors: Bennett, F Chris, Bennett, Mariko L, Yaqoob, Fazeela, Mulinyawe, Sara B, Grant, Gerald A, Gephart, Melanie Hayden, Plowey, Edward D, Barres, Ben A
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023731/
https://ncbi.nlm.nih.gov/pubmed/29861285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.05.014
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