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A combination of ontogeny and CNS environment establishes microglial identity.
Microglia, the brain’s resident macrophages, are dynamic CNS custodians with surprising origins in the extra-embryonic yolk sac. The consequences of their distinct ontogeny are unknown but critical to understanding and treating brain diseases. We created a brain macrophage transplantation system to...
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| Veröffentlicht in: | Neuron |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6023731/ https://ncbi.nlm.nih.gov/pubmed/29861285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.05.014 |
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