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Distinct Stages of Myelination Regulated by γ-Secretase and Astrocytes in a Rapidly Myelinating CNS Coculture System

Mechanistic studies of CNS myelination have been hindered by the lack of a rapidly myelinating culture system. Here we describe a versatile CNS coculture method that allows time-lapse microscopy and molecular analysis of distinct stages of myelination. Employing a culture architecture of reaggregate...

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Hlavní autoři: Watkins, Trent A., Emery, Ben, Mulinyawe, Sara, Barres, Ben A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650711/
https://ncbi.nlm.nih.gov/pubmed/19038214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.09.011
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