Covalent capture of a human O(6)-alkylguanine alkyltransferase–DNA complex using N(1),O(6)-ethanoxanthosine, a mechanism-based crosslinker
The DNA repair protein O(6)-alkylguanine alkyltransferase (AGT) is responsible for removing promutagenic alkyl lesions from exocyclic oxygens located in the major groove of DNA, i.e. the O(6) and O(4) positions of guanine and thymine. The protein carries out this repair reaction by transferring the...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60232/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11574685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.19.4025 |
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