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Applied molecular evolution of O(6)-benzylguanine-resistant DNA alkyltransferases in human hematopoietic cells
Applied molecular evolution is a rapidly developing technology that can be used to create and identify novel enzymes that nature has not selected. An important application of this technology is the creation of highly drug-resistant enzymes for cancer gene therapy. Seventeen O(6)-alkylguanine-DNA alk...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33144/ https://ncbi.nlm.nih.gov/pubmed/11296271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091601198 |
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