Applied molecular evolution of O(6)-benzylguanine-resistant DNA alkyltransferases in human hematopoietic cells

Applied molecular evolution is a rapidly developing technology that can be used to create and identify novel enzymes that nature has not selected. An important application of this technology is the creation of highly drug-resistant enzymes for cancer gene therapy. Seventeen O(6)-alkylguanine-DNA alk...

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Detaylı Bibliyografya
Asıl Yazarlar: Davis, Brian M., Encell, Lance P., Zielske, Steven P., Christians, Fred C., Liu, Lili, Friebert, Sarah E., Loeb, Lawrence A., Gerson, Stanton L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2001
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC33144/
https://ncbi.nlm.nih.gov/pubmed/11296271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091601198
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