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Driver gene mutations based clustering of tumors: methods and applications

MOTIVATION: Somatic mutations in proto-oncogenes and tumor suppressor genes constitute a major category of causal genetic abnormalities in tumor cells. The mutation spectra of thousands of tumors have been generated by The Cancer Genome Atlas (TCGA) and other whole genome (exome) sequencing projects...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Zhang, Wensheng, Flemington, Erik K, Zhang, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022677/
https://ncbi.nlm.nih.gov/pubmed/29950003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty232
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