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Driver gene mutations based clustering of tumors: methods and applications

MOTIVATION: Somatic mutations in proto-oncogenes and tumor suppressor genes constitute a major category of causal genetic abnormalities in tumor cells. The mutation spectra of thousands of tumors have been generated by The Cancer Genome Atlas (TCGA) and other whole genome (exome) sequencing projects...

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Bibliografiska uppgifter
I publikationen:Bioinformatics
Huvudupphovsmän: Zhang, Wensheng, Flemington, Erik K, Zhang, Kun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022677/
https://ncbi.nlm.nih.gov/pubmed/29950003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty232
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