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Driver gene mutations based clustering of tumors: methods and applications
MOTIVATION: Somatic mutations in proto-oncogenes and tumor suppressor genes constitute a major category of causal genetic abnormalities in tumor cells. The mutation spectra of thousands of tumors have been generated by The Cancer Genome Atlas (TCGA) and other whole genome (exome) sequencing projects...
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| Publié dans: | Bioinformatics |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6022677/ https://ncbi.nlm.nih.gov/pubmed/29950003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty232 |
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