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Gene prioritization using Bayesian matrix factorization with genomic and phenotypic side information

MOTIVATION: Most gene prioritization methods model each disease or phenotype individually, but this fails to capture patterns common to several diseases or phenotypes. To overcome this limitation, we formulate the gene prioritization task as the factorization of a sparsely filled gene-phenotype matr...

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Bibliografski detalji
Izdano u:Bioinformatics
Glavni autori: Zakeri, Pooya, Simm, Jaak, Arany, Adam, ElShal, Sarah, Moreau, Yves
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022676/
https://ncbi.nlm.nih.gov/pubmed/29949967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty289
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