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Gene prioritization using Bayesian matrix factorization with genomic and phenotypic side information

MOTIVATION: Most gene prioritization methods model each disease or phenotype individually, but this fails to capture patterns common to several diseases or phenotypes. To overcome this limitation, we formulate the gene prioritization task as the factorization of a sparsely filled gene-phenotype matr...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Principais autores: Zakeri, Pooya, Simm, Jaak, Arany, Adam, ElShal, Sarah, Moreau, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022676/
https://ncbi.nlm.nih.gov/pubmed/29949967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty289
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