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Haplotype phasing in single-cell DNA-sequencing data
MOTIVATION: Current technologies for single-cell DNA sequencing require whole-genome amplification (WGA), as a single cell contains too little DNA for direct sequencing. Unfortunately, WGA introduces biases in the resulting sequencing data, including non-uniformity in genome coverage and high rates...
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| Veröffentlicht in: | Bioinformatics |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6022575/ https://ncbi.nlm.nih.gov/pubmed/29950014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty286 |
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