Haplotype phasing in single-cell DNA-sequencing data

MOTIVATION: Current technologies for single-cell DNA sequencing require whole-genome amplification (WGA), as a single cell contains too little DNA for direct sequencing. Unfortunately, WGA introduces biases in the resulting sequencing data, including non-uniformity in genome coverage and high rates...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Satas, Gryte, Raphael, Benjamin J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Ismb 2018–Intelligent Systems for Molecular Biology Proceedings
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022575/
https://ncbi.nlm.nih.gov/pubmed/29950014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty286
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