Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

Lewy bodies commonly occur in Alzheimer’s disease, and Alzheimer’s disease pathology is frequent in Lewy body diseases, but the burden of co-pathologies across neurodegenerative diseases is unknown. We assessed the extent of tau, amyloid-β, α-synuclein and TDP-43 proteinopathies in 766 autopsied ind...

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Bibliografske podrobnosti
izdano v:Brain
Main Authors: Robinson, John L, Lee, Edward B, Xie, Sharon X, Rennert, Lior, Suh, EunRan, Bredenberg, Colin, Caswell, Carrie, Van Deerlin, Vivianna M, Yan, Ning, Yousef, Ahmed, Hurtig, Howard I, Siderowf, Andrew, Grossman, Murray, McMillan, Corey T, Miller, Bruce, Duda, John E, Irwin, David J, Wolk, David, Elman, Lauren, McCluskey, Leo, Chen-Plotkin, Alice, Weintraub, Daniel, Arnold, Steven E, Brettschneider, Johannes, Lee, Virginia M.-Y, Trojanowski, John Q
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022546/
https://ncbi.nlm.nih.gov/pubmed/29878075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy146
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