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BaxΔ2 sensitizes colorectal cancer cells to proteasome inhibitor-induced cell death

Proteasome inhibitors, such as bortezomib and carfilzomib, are FDA approved for the treatment of hemopoietic cancers, but recent studies have shown their great potential for treatment of solid tumors. BaxΔ2, a unique proapoptotic Bax isoform, promotes non-mitochondrial cell death and sensitizes canc...

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Bibliografiska uppgifter
I publikationen:Biochem Biophys Res Commun
Huvudupphovsmän: Mañas, Adriana, Chen, Wenjing, Nelson, Adam, Yao, Qi, Xiang, Jialing
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022363/
https://ncbi.nlm.nih.gov/pubmed/29291406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.12.156
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