Randomized, controlled, proof-of-concept trial of MK-7622 in Alzheimer's disease

INTRODUCTION: We evaluated the selective M1 muscarinic positive allosteric modulator, MK-7622, as adjunctive cognitive enhancing therapy in individuals with Alzheimer's disease. METHODS: A randomized, double-blind, proof-of-concept trial was performed. Participants with mild-to-moderate Alzheim...

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Pubblicato in:Alzheimers Dement (N Y)
Autori principali: Voss, Tiffini, Li, Jerry, Cummings, Jeffrey, Farlow, Martin, Assaid, Christopher, Froman, Samar, Leibensperger, Heather, Snow-Adami, Linda, McMahon, Kerry Budd, Egan, Michael, Michelson, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021552/
https://ncbi.nlm.nih.gov/pubmed/29955661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2018.03.004
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