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Clinical-scale production of cGMP compliant CD3/CD19 cell-depleted NK cells in the evolution of NK cell immunotherapy at a single institution

BACKGROUND: Allogeneic NK cell adoptive immunotherapy is a growing therapeutic option for patients. Clinical-scale production of NK cells using immunomagnetic selection complies with current good manufacturing practices (cGMPs) and allows for closed-system, automated purification. We report our expe...

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Bibliografiske detaljer
Udgivet i:Transfusion
Main Authors: Williams, Shelly M., Sumstad, Darin, Kadidlo, Diane, Curtsinger, Julie, Luo, Xianghua, Miller, Jeffrey S., McKenna, David H.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021208/
https://ncbi.nlm.nih.gov/pubmed/29532488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.14564
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