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β-Adrenergic receptor trafficking, degradation, and cell-surface expression are altered in dermal fibroblasts from hypertrophic scars

Burn trauma elevates catecholamines for up to 2 years and causes hypertrophic scarring. Propranolol, a non-specific ß1, ß2 adrenergic receptor (AR) inverse agonist, counters the hypermetabolic response to elevated catecholamines and may decrease hypertrophic scarring by an unknown mechanism. We inve...

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Bibliographische Detailangaben
Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Ayadi, Amina El, Prasai, Anesh, Wang, Ye, Herndon, David N, Finnerty, Celeste C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021177/
https://ncbi.nlm.nih.gov/pubmed/29476776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.01.037
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