Wird geladen...
Novel FFA1 (GPR40) agonists containing spirocyclic periphery: polar azine periphery as a driver of potency
A series of nine compounds based on 3-[4-(benzyloxy)phenyl]propanoic acid core containing a 1-oxa-9-azaspiro[5.5]undecane periphery was designed, synthesized and evaluated as free fatty acid 1 (FFA1 or GPR40) agonists. The spirocyclic appendages included in these compounds were inspired by LY2881835...
Gespeichert in:
| Veröffentlicht in: | J Enzyme Inhib Med Chem |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2016
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6021034/ https://ncbi.nlm.nih.gov/pubmed/27781494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2016.1230110 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|