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Quantitative methods to investigate the 4D dynamics of heterochromatic repair sites in Drosophila cells

Heterochromatin is mostly composed of long stretches of repeated DNA sequences prone to ectopic recombination during double-strand break (DSB) repair. In Drosophila, ‘safe’ homologous recombination (HR) repair of heterochromatic DSBs relies on a striking relocalization of repair sites to the nuclear...

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Dades bibliogràfiques
Publicat a:Methods Enzymol
Autors principals: Caridi, Christopher P., Delabaere, Laetitia, Tjong, Harianto, Hopp, Hannah, Das, Devika, Alber, Frank, Chiolo, Irene
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021022/
https://ncbi.nlm.nih.gov/pubmed/29523239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.11.033
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