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Quantitative methods to investigate the 4D dynamics of heterochromatic repair sites in Drosophila cells

Heterochromatin is mostly composed of long stretches of repeated DNA sequences prone to ectopic recombination during double-strand break (DSB) repair. In Drosophila, ‘safe’ homologous recombination (HR) repair of heterochromatic DSBs relies on a striking relocalization of repair sites to the nuclear...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Caridi, Christopher P., Delabaere, Laetitia, Tjong, Harianto, Hopp, Hannah, Das, Devika, Alber, Frank, Chiolo, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021022/
https://ncbi.nlm.nih.gov/pubmed/29523239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.11.033
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