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HDAC10 as a potential therapeutic target in ovarian cancer

OBJECTIVE: We analyzed histone deacetylase 10 (HDAC10) for function in the context of the DNA damage response in BRCA1-null ovarian cancer cells as well as evaluated the potential of general HDAC inhibitors in primary ovarian carcinoma cells. HDAC10 had previously been shown to be highly stimulatory...

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Podrobná bibliografie
Vydáno v:Gynecol Oncol
Hlavní autoři: Islam, Muhtadi M., Banerjee, Tapahsama, Packard, Colin Z., Kotian, Shweta, Selvendiran, Karuppaiyah, Cohn, David E., Parvin, Jeffrey D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020686/
https://ncbi.nlm.nih.gov/pubmed/28073598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2017.01.009
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