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NUSAP1 influences the DNA damage response by controlling BRCA1 protein levels

NUSAP1 has been reported to function in mitotic spindle assembly, chromosome segregation, and regulation of cytokinesis. In this study, we find that NUSAP1 has hitherto unknown functions in the key BRCA1-regulated pathways of double strand DNA break repair and centrosome duplication. Both these path...

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Detalhes bibliográficos
Main Authors: Kotian, Shweta, Banerjee, Tapahsama, Lockhart, Ainsley, Huang, Kun, Catalyurek, Umit V, Parvin, Jeffrey D
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026076/
https://ncbi.nlm.nih.gov/pubmed/24521615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28019
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