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The role of BRCA1 in DNA damage response

BRCA1 is a well-established tumor suppressor gene, which is frequently mutated in familial breast and ovarian cancers. The gene product of BRCA1 functions in a number of cellular pathways that maintain genomic stability, including DNA damage-induced cell cycle checkpoint activation, DNA damage repai...

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Detalles Bibliográficos
Main Authors: Wu, Jiaxue, Lu, Lin-Yu, Yu, Xiaochun
Formato: Artigo
Idioma:Inglês
Publicado: Higher Education Press 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078634/
https://ncbi.nlm.nih.gov/pubmed/21203981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0010-5
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