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The role of BRCA1 in DNA damage response
BRCA1 is a well-established tumor suppressor gene, which is frequently mutated in familial breast and ovarian cancers. The gene product of BRCA1 functions in a number of cellular pathways that maintain genomic stability, including DNA damage-induced cell cycle checkpoint activation, DNA damage repai...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Higher Education Press
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078634/ https://ncbi.nlm.nih.gov/pubmed/21203981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0010-5 |
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