Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics

Muraymycins are a subclass of antimicrobially active uridine-derived natural products. Biological data on several muraymycin analogues have already been reported, including some inhibitory in vitro activities towards their target protein, the bacterial membrane enzyme MraY. However, a structure-acti...

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Veröffentlicht in:ChemMedChem
Hauptverfasser: Koppermann, Stefan, Cui, Zheng, Fischer, Patrick D., Wang, Xiachang, Ludwig, Jannine, Thorson, Jon S., Van Lanen, Steven G., Ducho, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019934/
https://ncbi.nlm.nih.gov/pubmed/29438582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201700793
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