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Dual blockade of PI3K and MEK in combination with radiation in head and neck cancer
BACKGROUND AND PURPOSE: In this study we have combined fractionated radiation treatment (RT) with two molecular targeted agents active against key deregulated signaling pathways in head and neck cancer. MATERIALS AND METHODS: We used two molecularly characterized, low passage HNSCC cell lines of dif...
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| 發表在: | Clin Transl Radiat Oncol |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6019866/ https://ncbi.nlm.nih.gov/pubmed/30014041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctro.2018.04.003 |
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