Loading...

Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag

Frataxin gene (FXN) expression is reduced in Friedreich’s ataxia patients due to an increase in the number of GAA trinucleotides in intron 1. The frataxin protein, encoded by that gene, plays an important role in mitochondria’s iron metabolism. Platinum TALE (plTALE) proteins targeting the regulator...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Cherif, Khadija, Gérard, Catherine, Rousseau, Joël, Ouellet, Dominique L., Chapdelaine, Pierre, Tremblay, Jacques P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019861/
https://ncbi.nlm.nih.gov/pubmed/30195758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.04.009
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!