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Susceptibility of epithelial cells cultured from different regions of human cervix to HPV16-induced immortalization

Persistent infection with high-risk human papillomavirus (HPV) is a major risk factor for cervical cancer. Greater than 90% of these cancers originate in the cervical transformation zone (TZ), a narrow region of metaplastic squamous epithelium that develops at the squamocolumnar junction between the...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Deng, Han, Hillpot, Eric, Yeboah, Philomina, Mondal, Sumona, Woodworth, Craig D.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019754/
https://ncbi.nlm.nih.gov/pubmed/29944714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199761
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