Human Papillomavirus type 16 E6 and E 7 proteins alter NF-kB in cultured cervical epithelial cells and inhibition of NF-kB promotes cell growth and immortalization

The NF-kB family of transcription factors regulates important biological functions including cell growth, survival and the immune response. We found that Human Papillomavirus type 16 (HPV-16) E7 and E6/E7 proteins inhibited basal and TNF-alpha-inducible NF-kB activity in human epithelial cells cultu...

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Detalhes bibliográficos
Main Authors: Vandermark, Erik R., Deluca, Krysta A., Gardner, Courtney R., Marker, Daniel F., Schreiner, Cynthia N., Strickland, David A., Wilton, Katelynn M., Mondal, Sumona, Woodworth, Craig D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289550/
https://ncbi.nlm.nih.gov/pubmed/22284893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.12.023
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