Transforming growth factors beta 1 and 2 transcriptionally regulate human papillomavirus (HPV) type 16 early gene expression in HPV-immortalized human genital epithelial cells.

Human papillomavirus type 16 (HPV16) early proteins E6 and E7 have been implicated in maintenance of the malignant phenotype in cervical cancer. Transforming growth factors beta one and two (TGF betas 1 and 2), polypeptides that regulate cellular growth and differentiation, reversibly inhibited expr...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Woodworth, C D, Notario, V, DiPaolo, J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1990
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168964/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.10.4767-4775.1990
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